Medical Physics

Detectability of perfusion defect in five-dimensional gated-dynamic cardiac SPECT images

Xiaofeng Niu, Yongyi Yang, Michael A. King, and Miles N. Wernick
Purpose: In previous work, the authors developed and demonstrated the concept of an image reconstruction procedure aimed to unify gated and dynamic nuclear cardiac imaging, which the authors have termed five-dimensional (5D) SPECT. Gated imaging permits the clinician to evaluate wall motion and, th ... [Med. Phys. 37, 5102 (2010)] published Tue Aug 31, 2010.

Compressed sensing based cone-beam computed tomography reconstruction with a first-order method

Kihwan Choi, Jing Wang, Lei Zhu, Tae-Suk Suh, Stephen Boyd et al.
Purpose: This article considers the problem of reconstructing cone-beam computed tomography (CBCT) images from a set of undersampled and potentially noisy projection measurements. Methods: The authors cast the reconstruction as a compressed sensing problem based on [script-l] norm minimization con ... [Med. Phys. 37, 5113 (2010)] published Tue Aug 31, 2010.

Assessment of normal tissue complications following prostate cancer irradiation: Comparison of radiation treatment modalities using NTCP models

Rungdham Takam, Eva Bezak, Eric E. Yeoh, and Loredana Marcu
Purpose: Normal tissue complication probability (NTCP) of the rectum, bladder, urethra, and femoral heads following several techniques for radiation treatment of prostate cancer were evaluated applying the relative seriality and Lyman models. Methods: Model parameters from literature were used in ... [Med. Phys. 37, 5126 (2010)] published Tue Aug 31, 2010.

Improved accuracy of cortical bone mineralization measured by polychromatic microcomputed tomography using a novel high mineral density composite calibration phantom

Justin M. Deuerling, David J. Rudy, Glen L. Niebur, and Ryan K. Roeder
Purpose: Microcomputed tomography (micro-CT) is increasingly used as a nondestructive alternative to ashing for measuring bone mineral content. Phantoms are utilized to calibrate the measured x-ray attenuation to discrete levels of mineral density, typically including levels up to 1000 mg HA/cm, w ... [Med. Phys. 37, 5138 (2010)] published Tue Aug 31, 2010.

Comment on Monte Carlo dosimetry of Co HDR brachytherapy sources [Med. Phys. 30, 712721 (2003)]

T. Palani Selvam, Sridhar Sahoo, and R. S. Vishwakarma
Abstract not available. [Med. Phys. 37, 5146 (2010)] published Tue Aug 31, 2010.

Radiation Physics for Medical Physicists2nd ed

Ervin Podgorsak and William Hendee
Abstract not available. [Med. Phys. 37, 5148 (2010)] published Tue Aug 31, 2010.

A simple method for estimating the noise level in a signal region of an MR image

Michael C. Steckner
Purpose: A simple extension to the NEMA MS-1 difference of neighboring pixels SNR method is presented, which can accurately determine the noise level within a signal region over a wide range of noise levels, image nonuniformities, and artifact levels, as demonstrated by simple simulations and exper ... [Med. Phys. 37, 5072 (2010)] published Tue Aug 31, 2010.

Optimizing principal component models for representing interfraction variation in lung cancer radiotherapy

Ahmed M. Badawi, Elisabeth Weiss, William C. Sleeman, IV, Chenyu Yan, and Geoffrey D. Hugo
Purpose: To optimize modeling of interfractional anatomical variation during active breath-hold radiotherapy in lung cancer using principal component analysis (PCA). Methods: In 12 patients analyzed, weekly CT sessions consisting of three repeat intrafraction scans were acquired with active breath ... [Med. Phys. 37, 5080 (2010)] published Tue Aug 31, 2010.

Clinical application and validation of an iterative forward projection matching algorithm for permanent brachytherapy seed localization from conebeam-CT x-ray projections

Damodar Pokhrel, Martin J. Murphy, Dorin A. Todor, Elisabeth Weiss, and Jeffrey F. Williamson
Purpose: To experimentally validate a new algorithm for reconstructing the 3D positions of implanted brachytherapy seeds from postoperatively acquired 2D conebeam-CT (CBCT) projection images. Methods: The iterative forward projection matching (IFPM) algorithm finds the 3D seed geometry that minimi ... [Med. Phys. 37, 5092 (2010)] published Tue Aug 31, 2010.

An investigation of 4D cone-beam CT algorithms for slowly rotating scanners

Frank Bergner, Timo Berkus, Markus Oelhafen, Patrik Kunz, Tinsu Pan et al.
Purpose: To evaluate several algorithms for 4D cone-beam computed tomography (4D CBCT) with slow rotating devices. 4D CBCT is used to perform phase-correlated (PC) reconstructions of moving objects, such as breathing patients, for example. Such motion phase-dependent reconstructions are especially ... [Med. Phys. 37, 5044 (2010)] published Mon Aug 30, 2010.

Phantom-based experimental validation of computational fluid dynamics simulations on cerebral aneurysms

Qi Sun, Alexandra Groth, Matthias Bertram, Irina Waechter, Tom Bruijns et al.
Purpose: Recently, image-based computational fluid dynamics (CFD) simulation has been applied to investigate the hemodynamics inside human cerebral aneurysms. The knowledge of the computed three-dimensional flow fields is used for clinical risk assessment and treatment decision making. However, the ... [Med. Phys. 37, 5054 (2010)] published Mon Aug 30, 2010.

Quiescent period respiratory gating for PET/CT

Chi Liu, Adam Alessio, Larry Pierce, Kris Thielemans, Scott Wollenweber et al.
Purpose: To minimize respiratory motion artifacts, this work proposes quiescent period gating (QPG) methods that extract PET data from the end-expiration quiescent period and form a single PET frame with reduced motion and improved signal-to-noise properties. Methods: Two QPG methods are proposed ... [Med. Phys. 37, 5037 (2010)] published Mon Aug 30, 2010.

Assessment of variation in Elekta plastic spherical-calibration phantom and its impact on the Leksell Gamma Knife calibration

Josef Novotny, Jr., Jagdish P. Bhatnagar, Hyun-Tai Chung, Jonas Johansson, Greg Bednarz et al.
Purpose: Traditionally, the dose-rate calibration (output) of the Leksell Gamma Knife (LGK) unit is performed using a 160 mm diameter plastic spherical phantom provided by the vendor of the LGK, Elekta Instrument AB. The purpose of this study was to evaluate variations in the Elekta spherical phant ... [Med. Phys. 37, 5066 (2010)] published Mon Aug 30, 2010.

Hybrid referenceless and multibaseline subtraction MR thermometry for monitoring thermal therapies in moving organs

William A. Grissom, Viola Rieke, Andrew B. Holbrook, Yoav Medan, Michael Lustig et al.
Purpose: Magnetic resonance thermometry using the proton resonance frequency (PRF) shift is a promising technique for guiding thermal ablation. For temperature monitoring in moving organs, such as the liver and the heart, problems with motion must be addressed. Multi-baseline subtraction techniques ... [Med. Phys. 37, 5014 (2010)] published Mon Aug 30, 2010.

Event (error and near-miss) reporting and learning system for process improvement in radiation oncology

Sasa Mutic, R. Scott Brame, Swetha Oddiraju, Parag Parikh, Melisa A. Westfall et al.
Purpose: The value of near-miss and error reporting processes in many industries is well appreciated and typically can be supported with data that have been collected over time. While it is generally accepted that such processes are important in the radiation therapy (RT) setting, studies analyzing ... [Med. Phys. 37, 5027 (2010)] published Mon Aug 30, 2010.

A hierarchical evolutionary algorithm for multiobjective optimization in IMRT

Clay Holdsworth, Minsun Kim, Jay Liao, and Mark H. Phillips
Purpose: The current inverse planning methods for intensity modulated radiation therapy (IMRT) are limited because they are not designed to explore the trade-offs between the competing objectives of tumor and normal tissues. The goal was to develop an efficient multiobjective optimization algorithm ... [Med. Phys. 37, 4986 (2010)] published Fri Aug 27, 2010.

Detailed analysis of latencies in image-based dynamic MLC tracking

Per Rugaard Poulsen, Byungchul Cho, Amit Sawant, Dan Ruan, and Paul J. Keall
Purpose: Previous measurements of the accuracy of image-based real-time dynamic multileaf collimator (DMLC) tracking show that the major contributor to errors is latency, i.e., the delay between target motion and MLC response. Therefore the purpose of this work was to develop a method for detailed ... [Med. Phys. 37, 4998 (2010)] published Fri Aug 27, 2010.

A solid-state amorphous selenium avalanche technology for low photon flux imaging applications

M. M. Wronski, W. Zhao, A. Reznik, K. Tanioka, G. DeCrescenzo et al.
Purpose: The feasibility of a practical solid-state technology for low photon flux imaging applications was investigated. The technology is based on an amorphous selenium photoreceptor with a voltage-controlled avalanche multiplication gain. If this photoreceptor can provide sufficient internal gai ... [Med. Phys. 37, 4982 (2010)] published Fri Aug 27, 2010.

Comparison of three strategies in management of independent movement of the prostate and pelvic lymph nodes

Ping Xia, Peng Qi, Andrew Hwang, Erica Kinsey, Jean Pouliot et al.
Purpose: Concurrent irradiation of the prostate and pelvic lymph nodes is technically challenging due to treating one moving target and one immobile target. The purposes of this article are to propose a new management strategy and to compare this strategy to the conventional isocenter shift method ... [Med. Phys. 37, 5006 (2010)] published Fri Aug 27, 2010.

Feasibility of high temporal resolution breast DCE-MRI using compressed sensing theory

Haoyu Wang, Yanwei Miao, Kun Zhou, Yanming Yu, Shanglian Bao et al.
Purpose: To investigate the feasibility of high temporal resolution breast DCE-MRI using compressed sensing theory. Methods: Two experiments were designed to investigate the feasibility of using reference image based compressed sensing (RICS) technique in DCE-MRI of the breast. The first experimen ... [Med. Phys. 37, 4971 (2010)] published Fri Aug 27, 2010.

Response of lithium formate EPR dosimeters at photon energies relevant to the dosimetry of brachytherapy

Emelie Adolfsson, Gudrun Alm Carlsson, Jan-Erik Grindborg, Hakan Gustafsson, Eva Lund et al.
Purpose: To investigate experimentally the energy dependence of the detector response of lithium formate EPR dosimeters for photon energies below 1 MeV relative to that at Co energies. High energy photon beams are used in calibrating dosimeters for use in brachytherapy since the absorbed dose to wa ... [Med. Phys. 37, 4946 (2010)] published Thu Aug 26, 2010.

An MCNPX Monte Carlo model of a discrete spot scanning proton beam therapy nozzle

Gabriel O. Sawakuchi, Dragan Mirkovic, Luis A. Perles, Narayan Sahoo, X. Ron Zhu et al.
Purpose: The purposes of this study were to validate a discrete spot scanning proton beam nozzle using the Monte Carlo (MC) code MCNPX and use the MC validated model to investigate the effects of a low-dose envelope, which surrounds the beam's central axis, on measurements of integral depth dose (I ... [Med. Phys. 37, 4960 (2010)] published Thu Aug 26, 2010.

A fast optimization algorithm for multicriteria intensity modulated proton therapy planning

Wei Chen, David Craft, Thomas M. Madden, Kewu Zhang, Hanne M. Kooy et al.
Purpose: To describe a fast projection algorithm for optimizing intensity modulated proton therapy (IMPT) plans and to describe and demonstrate the use of this algorithm in multicriteria IMPT planning. Methods: The authors develop a projection-based solver for a class of convex optimization proble ... [Med. Phys. 37, 4938 (2010)] published Thu Aug 26, 2010.

Technical Note: Calculation of normal tissue complication probability using Gaussian error function model

James C. L. Chow, Daniel Markel, and Runqing Jiang
Purpose: The Gaussian error function was first used and verified in normal tissue complication probability (NTCP) calculation to reduce the dose-volume histogram (DVH) database by replacing the dose-volume bin set with the error function parameters for the differential DVH (dDVH). Methods: Seven-b ... [Med. Phys. 37, 4924 (2010)] published Thu Aug 26, 2010.

Assessment of 2D and 3D fractal dimension measurements of trabecular bone from high-spatial resolution magnetic resonance images at 3 T

Angel Alberich-Bayarri, Luis Marti-Bonmati, Maria Angeles Perez, Roberto Sanz-Requena, Juan Jose Lerma-Garrido et al.
Purpose: In vivo two-dimensional (2D) fractal dimension (D) analysis of the cancellous bone at 1.5 T has been related to bone structural complexity and shown to be a potential imaging-based biomarker for osteoporosis. The objectives of this study were to assess at 3 T the in vivo feasibility of thr ... [Med. Phys. 37, 4930 (2010)] published Thu Aug 26, 2010.

Effect of longitudinal magnetic fields on a simulated in-line 6 MV linac

J. St. Aubin, D. M. Santos, S. Steciw, and B. G. Fallone
Purpose: Linac-magnetic resonance (MR) systems have been proposed in order to achieve real-time image guided radiotherapy. The design of a new linac-MR system with the in-line 6 MV linac generating x-rays along the symmetry axis of an open MR imager is outlined. This new design allows for a greater ... [Med. Phys. 37, 4916 (2010)] published Tue Aug 24, 2010.

4D XCAT phantom for multimodality imaging research

W. P. Segars, G. Sturgeon, S. Mendonca, Jason Grimes, and B. M. W. Tsui
Purpose: The authors develop the 4D extended cardiac-torso (XCAT) phantom for multimodality imaging research. Methods: Highly detailed whole-body anatomies for the adult male and female were defined in the XCAT using nonuniform rational B-spline (NURBS) and subdivision surfaces based on segmentati ... [Med. Phys. 37, 4902 (2010)] published Tue Aug 24, 2010.

Overcorrection of iodinated contrast attenuation in SPECT-CT: Phantom studies

Dacian V. Bonta and Richard L. Wahl
Purpose: The authors investigated the effects of iodinated contrast agents on the quantification of radioactivity obtained using a combined single photon emission tomography (SPECT) and high resolution 16 slice computed tomography (CT) scanner. Methods: Two conditions were evaluated: Contrast medi ... [Med. Phys. 37, 4897 (2010)] published Mon Aug 23, 2010.

Direction-dependent localization errors in SPECT images

Justin Roper, James Bowsher, and Fang-Fang Yin
Purpose: Single photon emission computed tomography (SPECT) is being investigated for imaging inside radiation therapy treatment rooms to localize biological targets. Here, computer simulations were used to analyze locational and directional dependencies in localization errors and to assess the eff ... [Med. Phys. 37, 4886 (2010)] published Mon Aug 23, 2010.

Moving target irradiation with fast rescanning and gating in particle therapy

Takuji Furukawa, Taku Inaniwa, Shinji Sato, Toshiyuki Shirai, Shinichiro Mori et al.
Purpose: In moving target irradiation with pencil beam scanning, the interplay effect between the target motion and the scanned beam is a problem because this effect causes over or under dosage in the target volume. To overcome this, we have studied rescanning using a gating technique. Methods: A ... [Med. Phys. 37, 4874 (2010)] published Mon Aug 23, 2010.

Dosimetric evaluation of the OneDose MOSFET for measuring kilovoltage imaging dose from image-guided radiotherapy procedures

George X. Ding and Charles W. Coffey
Purpose: The purpose of this study is to investigate the feasibility of using a single-use dosimeter, OneDose MOSFET designed for in vivo patient dosimetry, for measuring the radiation dose from kilovoltage (kV) x rays resulting from image-guided procedures. Methods: The OneDose MOSFET dosimeters ... [Med. Phys. 37, 4880 (2010)] published Mon Aug 23, 2010.

QA for helical tomotherapy: Report of the AAPM Task Group 148

Katja M. Langen, Niko Papanikolaou, John Balog, Richard Crilly, David Followill et al.
Helical tomotherapy is a relatively new modality with integrated treatment planning and delivery hardware for radiation therapy treatments. In view of the uniqueness of the hardware design of the helical tomotherapy unit and its implications in routine quality assurance, the Therapy Physics Committ ... [Med. Phys. 37, 4817 (2010)] published Fri Aug 20, 2010.

A gamma dose distribution evaluation technique using the k-d tree for nearest neighbor searching

Jiankui Yuan and Weimin Chen
Purpose: The authors propose an algorithm based on the k-d tree for nearest neighbor searching to improve the gamma calculation time for 2D and 3D dose distributions. Methods: The gamma calculation method has been widely used for comparisons of dose distributions in clinical treatment plans and qu ... [Med. Phys. 37, 4868 (2010)] published Fri Aug 20, 2010.

Radiation dose estimation using preclinical imaging with I-metaiodobenzylguanidine (MIBG) PET

Chang-Lae Lee, Hilla Wahnishe, George A. Sayre, Hyo-Min Cho, Hee-Joung Kim et al.
Purpose: A pretherapy I-metaiodobenzylguanidine (MIBG) positron emission tomography (PET)/computed tomography (CT) provides a potential method to estimate radiation dose to normal organs, as well as tumors prior to I-MIBG treatment of neuroblastoma or pheochromocytoma. The aim of this work was to e ... [Med. Phys. 37, 4861 (2010)] published Fri Aug 20, 2010.

The inter- and intrafraction reproducibilities of three common IMRT delivery techniques

Courtney R. Buckey, Sotirios Stathakis, and Niko Papanikolaou
Purpose: Intensity modulated radiation therapy (IMRT) treatment delivery requires higher precision than conventional 3D treatment delivery because of the sensitivity of the resulting dose to small geometric misalignment of the modulated beamlets. The chosen treatment delivery technique will affect ... [Med. Phys. 37, 4854 (2010)] published Fri Aug 20, 2010.

QA procedures for multimodality preclinical tumor drug response testing

Yongsook C. Lee, Beth A. Goins, and Gary D. Fullerton
Purpose: There are growing expectations that imaging biomarkers for tumor therapeutic drug response assessment will speed up preclinical testing of anticancer drugs in rodent models. The only imaging biomarker presently approved by the U.S. Food and Drug Administration is tumor size measurement bas ... [Med. Phys. 37, 4806 (2010)] published Thu Aug 19, 2010.

In vivo imaging and treatment of solid tumor using integrated photoacoustic imaging and high intensity focused ultrasound system

Huizhong Cui and Xinmai Yang
Purpose: The purpose of this study is to show the feasibility of combined contrast imaging and treatment of solid tumor in vivo by an integrated photoacoustic imaging and high intensity focused ultrasound (HIFU) system. Methods: During this study, photoacoustic imaging was performed to identify th ... [Med. Phys. 37, 4777 (2010)] published Thu Aug 19, 2010.

Implementation of radiochromic film dosimetry protocol for volumetric dose assessments to various organs during diagnostic CT procedures

Samuel Brady, Terry Yoshizumi, Greta Toncheva, and Donald Frush
Purpose: The authors present a means to measure high-resolution, two-dimensional organ dose distributions in an anthropomorphic phantom of heterogeneous tissue composition using XRQA radiochromic film. Dose distributions are presented for the lungs, liver, and kidneys to demonstrate the organ volum ... [Med. Phys. 37, 4782 (2010)] published Thu Aug 19, 2010.

Longitudinal assessment of lung cancer progression in the mouse using in vivo micro-CT imaging

Eman Namati, Jacqueline Thiesse, Jessica C. Sieren, Alan Ross, Eric A. Hoffman et al.
Purpose: Small animal micro-CT imaging is being used increasingly in preclinical biomedical research to provide phenotypic descriptions of genomic models. Most of this imaging is coincident with animal death and is used to show the extent of disease as an end point. Longitudinal imaging overcomes t ... [Med. Phys. 37, 4793 (2010)] published Thu Aug 19, 2010.

Comparison between diffusion-weighted imaging, T-weighted, and postcontrast T-weighted imaging after MR-guided, high intensity, focused ultrasound treatment of uterine leiomyomata: Preliminary results

Michael A. Jacobs, David H. Gultekin, and Hyun S. Kim
Purpose: To investigate the comparison between diffusion-weighted imaging (DWI), T-weighted imaging, (TWI) and contrast T-weighted imaging (cTWI) in uterine leiomyoma following treatment by magnetic resonance imaging-guided, high intensity focused ultrasound surgery (MRg-HIFUS). Methods: Twenty on ... [Med. Phys. 37, 4768 (2010)] published Wed Aug 18, 2010.

The accuracy and safety aspects of a novel robotic needle guide manipulator to perform transrectal prostate biopsies

Martijn G. Schouten, Janneke Ansems, W. Klaas Jan Renema, Dennis Bosboom, Tom W. J. Scheenen et al.
Purpose: To introduce a new in-house developed pneumatically controlled magnetic field compatible manipulator as an aid to perform magnetic resonance (MR)-guided biopsies of the prostate. Methods: A pneumatic controlled manipulator with five degrees of freedom constructed of plastic to achieve mag ... [Med. Phys. 37, 4744 (2010)] published Tue Aug 17, 2010.

Waveguide detuning caused by transverse magnetic fields on a simulated in-line 6 MV linac

J. St. Aubin, S. Steciw, and B. G. Fallone
Purpose: Due to the close proximity of the linear accelerator (linac) to the magnetic resonance (MR) imager in linac-MR systems, it will be subjected to magnet fringe fields larger than the Earth's magnetic field of 5 x 10 T. Even with passive or active shielding designed to reduce these fields, s ... [Med. Phys. 37, 4751 (2010)] published Tue Aug 17, 2010.

A wavelet-based SPECT reconstruction algorithm for nonuniformly attenuated Radon transform

Junhai Wen and Lingkai Kong
Purpose: Single photon emission computed tomography (SPECT) is a tomography technique that can greatly show information about the metabolic activity in the body and improve the clinical diagnosis. In SPECT, because of photoelectric absorption and Compton scattering, the emitted gamma photons are at ... [Med. Phys. 37, 4762 (2010)] published Tue Aug 17, 2010.

Dosimetric impact of an Ir brachytherapy source cable length modeled using a grid-based Boltzmann transport equation solver

Justin K. Mikell and Firas Mourtada
Purpose: To evaluate the dose distributions of an Ir source (model VS2000) in homogeneous water geometry calculated using a deterministic grid-based Boltzmann transport equation solver (GBBS) in the commercial treatment planning system (TPS) (BRACHYVISION-ACUROS v8.8). Methods: Using percent dose ... [Med. Phys. 37, 4733 (2010)] published Tue Aug 17, 2010.

Comparison of GEANT4 very low energy cross section models with experimental data in water

S. Incerti, A. Ivanchenko, M. Karamitros, A. Mantero, P. Moretto et al.
Purpose: The GEANT4 general-purpose Monte Carlo simulation toolkit is able to simulate physical interaction processes of electrons, hydrogen and helium atoms with charge states (H, H) and (He, He, He), respectively, in liquid water, the main component of biological systems, down to the electron vol ... [Med. Phys. 37, 4692 (2010)] published Tue Aug 17, 2010.

Magnetic decoupling of the linac in a low field biplanar linac-MR system

J. St. Aubin, S. Steciw, and B. G. Fallone
Purpose: The integration of a low field biplanar magnetic resonance (MR) imager and linear accelerator (linac) causes magnetic interference at the linac due to the MR fringe fields. In order to eliminate this interference, passive and active magnetic shielding designs are investigated. Methods: Th ... [Med. Phys. 37, 4755 (2010)] published Tue Aug 17, 2010.

A PET supersets data framework for exploitation of known motion in image reconstruction

Jeroen Verhaeghe and Andrew J. Reader
Purpose: Motion during PET data acquisition is either introduced by design (e.g., couch wobble to enrich data sampling) or through unintentional motion of the object under study (e.g., subject head motion). Prior to this present work, such effects have been considered within distinctly different fr ... [Med. Phys. 37, 4709 (2010)] published Tue Aug 17, 2010.

Lung dosimetry in a linac-MRI radiotherapy unit with a longitudinal magnetic field

C. Kirkby, B. Murray, S. Rathee, and B. G. Fallone
Purpose: There is interest in developing linac-MR systems for MRI-guided radiation therapy. To date, the designs for such linac-MR devices have been restricted to a transverse geometry where the static magnetic field is oriented perpendicular to the direction of the incident photon beam. This work ... [Med. Phys. 37, 4722 (2010)] published Tue Aug 17, 2010.

Dosimetric characterization of a multileaf collimator for a new four-dimensional image-guided radiotherapy system with a gimbaled x-ray head, MHI-TM2000

Mitsuhiro Nakamura, Akira Sawada, Yoshitomo Ishihara, Kenji Takayama, Takashi Mizowaki et al.
Purpose: To present the dosimetric characterization of a multileaf collimator (MLC) for a new four-dimensional image-guided radiotherapy system with a gimbaled x-ray head, MHI-TM2000. Methods: MHI-TM2000 has an x-ray head composed of an ultrasmall linear accelerator guide and a system-specific MLC ... [Med. Phys. 37, 4684 (2010)] published Mon Aug 16, 2010.

Computerized assessment of pulmonary fissure integrity using high resolution CT

Jiantao Pu, Carl Fuhrman, Janet Durick, Joseph K. Leader, Amy Klym et al.
Purpose: Knowledge of pulmonary interlobar fissure integrity is of interest in a number of clinical and investigational applications. The authors developed and tested a high resolution CT based automated computerized scheme for this purpose. Methods: The fissure integrity assessment scheme consist ... [Med. Phys. 37, 4661 (2010)] published Mon Aug 16, 2010.